Pre-treatment with meloxicam prevents the spinal inflammation and oxidative stress in DRG neurons that accompany painful cervical radiculopathy

S Kartha, CL Weisshaar, BH Philips, BA Winkelstein - Neuroscience, 2018 - Elsevier
… Even a transient compression of the nerve root can produce … immunohistochemistry in spinal
tissue from rats receiving … may alleviate pain by reducing inflammation-induced oxidative …

Nerve root compression increases spinal astrocytic vimentin in parallel with sustained pain and endothelial vimentin in association with spinal vascular …

JR Smith, J Lee, BA Winkelstein - Spine, 2017 - journals.lww.com
… cord tissue was harvested at days 1 and 7 after a unilateral nerve root compression in rats
transient nerve root compression induces mechanical hyperalgesia and mechanical allodynia

[HTML][HTML] Developmental changes in pain and spinal immune gene expression after radicular trauma in the rat

GA Barr, S Wang, CL Weisshaar… - Frontiers in …, 2016 - frontiersin.org
… and mechanical allodynia 1 day after compression injuryrat models of transient cervical
nerve or root compression and … more transient injury, we induced the compression injury at …

Chronic cervical radiculopathic pain is associated with increased excitability and hyperpolarization-activated current (Ih) in large-diameter dorsal root …

DL Liu, X Wang, WG Chu, N Lu, WJ Han… - … Pain, 2017 - journals.sagepub.com
… Whether cervical radiculopathic pain condition induces plastic changes of large-diameter …
study demonstrated that mechanical allodynia in a model of cervical radiculopathy in rats, is …

[HTML][HTML] Electroacupuncture alleviates hyperalgesia by regulating CB1 receptor of spinal cord in incisional neck pain rats

J Wang, J Zhang, Y Gao, Y Chen, C Duanmu… - Evidence-Based …, 2021 - hindawi.com
… c-fiber induced discharge of neurons in the spinal dorsal … allodynia and caused persistent
overexpression of glial fibrillary … Only those rats with transient forelimb paresis after lidocaine …

Use of the rat grimace scale to evaluate neuropathic pain in a model of cervical radiculopathy

BH Philips, CL Weisshaar… - Comparative …, 2017 - ingentaconnect.com
… A transient compression of the right C7 dorsal nerve root is … mechanical and thermal
hyperalgesia and allodynia in the … ,50 and painful nerve root compression also induces spinal glial

Bone mesenchymal stem cells attenuate radicular pain by inhibiting microglial activation in a rat noncompressive disk herniation model

X Huang, W Wang, X Liu, Y Xi, J Yu, X Yang… - Cell and tissue …, 2018 - Springer
mechanical allodynia and downregulate the expression of proinflammatory cytokines by
inhibiting microglial activation in the spinal dorsal horn in a rat … on nerve root pain induced by …

Whole‐body vibration induces pain and lumbar spinal inflammation responses in the rat that vary with the vibration profile

ME Zeeman, S Kartha… - Journal of Orthopaedic …, 2016 - Wiley Online Library
neck and back pain in humans, and to forepaw mechanical … , activation of astrocytes and
microglia in the cervical spinal cord … The transient, recovering allodynia that is observed here is …

The role of spinal thrombin through protease-activated receptor 1 in hyperalgesia after neural injury

JR Smith, BA Winkelstein - Journal of Neurosurgery: Spine, 2017 - thejns.org
… a transient nerve root compression that also induces hyperalgesia, … compression in the
rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful

Techniques for multiscale neuronal regulation via therapeutic materials and drug design

S Zhang, S Kartha, J Lee… - … Biomaterials Science & …, 2017 - ACS Publications
… a transient compression of the nerve root can produce sustained … factors in salmon fibrin
can reduce the pain that is induced by mechanical trauma after nerve root compression in a rat